Irinotecan hydrochloride

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Indications Phases 4

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Colorectal neoplasms	D015179	—	—	162	469	129	13	64	748
Neoplasms	D009369	—	C80	195	114	26	1	12	300
Adenocarcinoma	D000230	—	—	66	138	32	1	12	224
Stomach neoplasms	D013274	EFO_0003897	C16	34	83	22	4	9	140
Carcinoma	D002277	—	C80.0	35	74	22	2	3	122
Neoplasm metastasis	D009362	EFO_0009708	—	19	58	27	3	18	116
Rectal neoplasms	D012004	—	—	23	66	20	2	11	113
Lung neoplasms	D008175	—	C34.90	28	72	12	3	4	105
Esophageal neoplasms	D004938	—	C15	16	57	13	1	5	85
Colonic neoplasms	D003110	—	C18	24	45	18	1	8	84

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Indications Phases 3

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Pancreatic neoplasms	D010190	EFO_0003860	C25	91	182	38	—	24	289
Recurrence	D012008	—	—	29	43	10	—	3	74
Pancreatic ductal carcinoma	D021441	—	—	20	32	6	—	3	54
Neuroblastoma	D009447	EFO_0000621	—	28	30	2	—	—	51
Non-small-cell lung carcinoma	D002289	—	—	23	33	1	—	2	50
Sarcoma	D012509	—	—	20	29	5	—	4	50
Glioblastoma	D005909	EFO_0000515	—	21	27	3	—	—	43
Breast neoplasms	D001943	EFO_0003869	C50	15	24	1	—	5	42
Ewing sarcoma	D012512	EFO_0000173	—	15	21	2	—	2	33
Esophageal squamous cell carcinoma	D000077277	—	—	6	20	9	—	—	32

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Indications Phases 2

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Glioma	D005910	EFO_0000520	—	20	26	—	—	—	40
Central nervous system neoplasms	D016543	—	—	17	14	—	—	1	27
Nervous system neoplasms	D009423	—	—	15	14	—	—	—	24
Ovarian neoplasms	D010051	EFO_0003893	C56	10	10	—	—	1	19
Triple negative breast neoplasms	D064726	—	—	10	6	—	—	—	15
Lymphoma	D008223	—	C85.9	9	4	—	—	—	13
Astrocytoma	D001254	EFO_0000271	—	8	7	—	—	—	13
Gliosarcoma	D018316	—	—	6	6	—	—	—	11
Ovarian epithelial carcinoma	D000077216	—	—	6	5	—	—	—	10
Medulloblastoma	D008527	—	—	4	8	—	—	—	10

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Indications Phases 1

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Precursor cell lymphoblastic leukemia-lymphoma	D054198	—	C91.0	3	—	—	—	1	4
Gastrointestinal stromal tumors	D046152	EFO_0000505	C49.A	4	—	—	—	—	4
Prostatic neoplasms	D011471	—	C61	4	—	—	—	—	4
Castration-resistant prostatic neoplasms	D064129	—	—	3	—	—	—	—	3
Myeloid leukemia acute	D015470	—	C92.0	2	—	—	—	1	3
Large b-cell lymphoma diffuse	D016403	—	C83.3	3	—	—	—	—	3
Myeloid leukemia	D007951	—	C92	1	—	—	—	1	2
Acute disease	D000208	—	—	1	—	—	—	1	2
B-cell chronic lymphocytic leukemia	D015451	—	C91.1	2	—	—	—	—	2
Chondrosarcoma	D002813	—	—	2	—	—	—	—	2

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Indications Without Phase

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Prognosis	D011379	—	—	—	—	—	—	2	2
Lymphoid leukemia	D007945	—	C91	—	—	—	—	1	1
Body weight	D001835	EFO_0004338	—	—	—	—	—	1	1
Weight loss	D015431	—	—	—	—	—	—	1	1
Hypertension	D006973	EFO_0000537	I10	—	—	—	—	1	1
Chemoradiotherapy	D059248	—	—	—	—	—	—	1	1
Brain death	D001926	—	G93.82	—	—	—	—	1	1
Mucositis	D052016	EFO_1001898	—	—	—	—	—	1	1
Male breast neoplasms	D018567	—	—	—	—	—	—	1	1
Ultrasonic therapy	D014464	—	—	—	—	—	—	1	1