Irinotecan hydrochloride

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Indications Phases 4

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Colorectal neoplasms	D015179	—	—	169	487	135	13	63	775
Neoplasms	D009369	—	C80	192	108	26	1	13	298
Rectal neoplasms	D012004	—	—	32	108	34	3	12	176
Colonic neoplasms	D003110	—	C18	39	90	32	1	9	153
Stomach neoplasms	D013274	EFO_0003897	C16	38	87	22	4	8	145
Neoplasm metastasis	D009362	EFO_0009708	—	37	66	26	2	15	135
Adenocarcinoma	D000230	—	—	33	87	11	1	7	123
Lung neoplasms	D008175	—	C34.90	29	59	9	3	3	92
Small cell lung carcinoma	D055752	—	—	25	50	12	3	5	81
Carcinoma	D002277	—	C80.0	20	37	8	1	2	61

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Indications Phases 3

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Pancreatic neoplasms	D010190	EFO_0003860	C25	107	194	44	—	26	319
Esophageal neoplasms	D004938	—	C15	15	51	7	—	2	70
Pancreatic ductal carcinoma	D021441	—	—	28	43	8	—	3	68
Recurrence	D012008	—	—	23	32	9	—	3	60
Non-small-cell lung carcinoma	D002289	—	—	25	36	1	—	2	55
Neuroblastoma	D009447	EFO_0000621	—	29	33	4	—	—	55
Glioblastoma	D005909	EFO_0000515	—	24	31	3	—	—	49
Sarcoma	D012509	—	—	16	26	5	—	4	44
Esophageal squamous cell carcinoma	D000077277	—	—	9	25	11	—	—	42
Breast neoplasms	D001943	EFO_0003869	C50	17	21	1	—	4	41

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Indications Phases 2

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Glioma	D005910	EFO_0000520	—	21	27	—	—	—	41
Central nervous system neoplasms	D016543	—	—	20	16	—	—	1	30
Ovarian neoplasms	D010051	EFO_0003893	C56	14	10	—	—	1	23
Astrocytoma	D001254	EFO_0000271	—	11	10	—	—	—	19
Gliosarcoma	D018316	—	—	8	9	—	—	—	16
Triple negative breast neoplasms	D064726	—	—	10	6	—	—	—	15
Medulloblastoma	D008527	—	—	7	11	—	—	—	14
Nervous system neoplasms	D009423	—	—	8	11	—	—	—	14
Oligodendroglioma	D009837	EFO_0000631	—	7	6	—	—	—	13
Lymphoma	D008223	—	C85.9	9	4	—	—	—	12

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Indications Phases 1

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Precursor cell lymphoblastic leukemia-lymphoma	D054198	—	C91.0	4	—	—	—	1	5
Gastrointestinal stromal tumors	D046152	EFO_0000505	C49.A	5	—	—	—	—	5
Prostatic neoplasms	D011471	—	C61	4	—	—	—	—	4
Large b-cell lymphoma diffuse	D016403	—	C83.3	4	—	—	—	—	4
Castration-resistant prostatic neoplasms	D064129	—	—	3	—	—	—	—	3
Myeloid leukemia acute	D015470	—	C92.0	2	—	—	—	1	3
B-cell chronic lymphocytic leukemia	D015451	—	C91.1	3	—	—	—	—	3
Hodgkin disease	D006689	—	C81	3	—	—	—	—	3
Burkitt lymphoma	D002051	—	C83.7	3	—	—	—	—	3
Large-cell lymphoma immunoblastic	D016400	—	—	3	—	—	—	—	3

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Indications Without Phase

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Prognosis	D011379	—	—	—	—	—	—	2	2
Lymphoid leukemia	D007945	—	C91	—	—	—	—	1	1
Body weight	D001835	EFO_0004338	—	—	—	—	—	1	1
Hypertension	D006973	EFO_0000537	I10	—	—	—	—	1	1
Chemoradiotherapy	D059248	—	—	—	—	—	—	1	1
Acne vulgaris	D000152	EFO_0003894	L70	—	—	—	—	1	1
Brain death	D001926	—	G93.82	—	—	—	—	1	1
Mucositis	D052016	EFO_1001898	—	—	—	—	—	1	1
Ultrasonic therapy	D014464	—	—	—	—	—	—	1	1
Multiple primary neoplasms	D009378	—	—	—	—	—	—	1	1